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Pycamilon and it's Place in the Group of
Well-Known Nootropic Drugs
[Article in Russian]
Institute of Pharmacology,
8, Baltiyskaya St., Moscow, 125315, USSR
Abstract
Pycamilon - N-nicotinoyl-GABA is a new vasoactive drug with nootropic
properties. It has anti-amnesic activity on two models of amnesia of passive
avoidance response, caused by maximum electro shock and scopolamine on mice.
Pycamilon increases exploratory behavior in open field. In comparison with the known nootropic drugs,
pycamilon produces a specific antiamnestic effecy in lower doses, than piracetam, etiracetam, aniracetam.
Effects of deanol, aceglumat, centrophenoxine, and pycamilon, received in the same doses, are similar. But
pycamilon is less potent than nicergoline.
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